Gloucester have three Wales starters with Anscombe joined by scrum-half Tomos Williams and centre Max Llewellyn.
Wing Josh Hathaway and lock Freddie Thomas are additionally within the squad, whereas forwards coach Rhys Thomas has been concerned within the backroom employees.
England will arrive on the Principality Stadium as title contenders, though a bonus-point France victory in opposition to Scotland afterward Saturday evening will assure Les Bleus prime spot.
Anscombe admits a Wales win would give him some bragging rights when the gamers return to Gloucester.
“It could make going into coaching a bit extra fulfilling,” mentioned Anscombe.
“You need not construct this sport up and England are coming right here with an opportunity to do one thing as properly.
“England within the stadium is all the time a bit completely different. We all know there’s going to be an incredible buzz and we might all need to give the followers one thing to cheer about.”
Anscombe’s future at Kingsholm is unsure after just one season, with Eire fly-half Ross Byrne signing for Gloucester.
“The Six Nations is such a singular competitors and having are available in midway by, it has been so full-on for the final three weeks we’re simply making an attempt to play the sport and what wants to vary,” mentioned Anscombe.
“My solely focus has been on having fun with pulling on the pink jersey as a result of once you get to my age you do not know what number of instances you’ll get an opportunity.
“For me it is simply having fun with the second, taking part in for Wales and I’ll maintain the longer term within the subsequent few weeks.”
